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Autophagic vacuoles in experimental atrophy

Identifieur interne : 003B57 ( Main/Exploration ); précédent : 003B56; suivant : 003B58

Autophagic vacuoles in experimental atrophy

Auteurs : Solon Cole [États-Unis, Suisse] ; Alex Matter [États-Unis, Suisse] ; Morris J. Karnovsky [États-Unis, Suisse]

Source :

Experimental and Molecular Pathology [ 0014-4800 ] ; 1971.

RBID : ISTEX:65292F482A3F13DE1FC8B22E8781A5D7AFC06583

English descriptors

Teeft :
- Acid phosphatase, Acid phosphatase reaction, Amer, Arstila, Atrophy, Autophagic, Autophagic vacuole, Autophagic vacuoles, Average diameter, Bile canaliculus, Biol, Cell biol, Cell diameter, Cell diameter measurements, Cell size, Cellular constituents, Control animals, Control livers, Cytoplasmic, Days postligation, Dense bodies, Double membranes, Electron micrographs, Electron microscope, Electron microscopy, Endoplasmic, Endoplasmic reticulum, Experimental animal, Experimental atrophy, Extracellular space, Fine structure, Focal dilatation, Glass slides, Glycogen, Golgi, Golgi apparatus, Hepatic, Hepatic cell, Hours postligation, Large clumps, Large vacuoles, Ligated, Ligated lobe, Ligated lobes, Ligation, Liquid level, Liver, Liver atrophy, Liver cell, Liver lobe, Liver mass, Lobe, Lysosome, Lysosome concept, Minutes postligation, Mitochondrion, Multiple membranes, Neutral polysaccharides, Nonligated, Nonligated counterpart, Nonligated counterpart lobe, Nonligated lobe, Nonligated lobes, Nonligated portions, Nonoperated controls, Numerous autophagic vacuoles, Osmium tetroxide, Oxygenating tube, Pathol, Phase contrast, Phosphate buffer, Portal, Portal supply, Portal vein, Portal vein ligation, Postligated lobes, Postligation, Prominent network, Reticulum, Rough endoplasmic reticulum, Same animal, Single membranes, Small vesicle, Smooth endoplasmic reticulum, Stellate slits, Time interval, Time postligation, Total liver weight, Trump, Unit area, Vacuole, Various organs, Various time intervals, Vena cava, Weight loss, Weight measurements.

Abstract

Abstract: The process of liver atrophy has been studied in an experimental model following occlusion of the portal supply to the right posterior lobe of the rat. The striking feature of these observations is the swift onset of the process of atrophy as evidenced by the rapid formation of autophagic vacuoles. Within 15 minutes there is a significant increase in the number of autophagic vacuoles. In 30 minutes, in addition, there is formation of intracellular “slits.” Autophagic vacuoles reach their peak number at 2 hours. They appear to arise from both smooth and rough endoplasmic reticulum, at first near the Golgi apparatus. Further, at 2 hours there is a significant decrease in cell size, and by the hour six there is a significant decrease in cell mass. Glycogen decreases markedly at 2 hours, but reappears in 3 to 7 days in clumps about the periphery of the cell.

Url:

https://api.istex.fr/ark:/67375/6H6-MPRHL3RH-V/fulltext.pdf

DOI: 10.1016/0014-4800(71)90062-1

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<author><name sortKey="Karnovsky, Morris J" sort="Karnovsky, Morris J" uniqKey="Karnovsky M" first="Morris J." last="Karnovsky">Morris J. Karnovsky</name>
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<term>Acid phosphatase reaction</term>
<term>Amer</term>
<term>Arstila</term>
<term>Atrophy</term>
<term>Autophagic</term>
<term>Autophagic vacuole</term>
<term>Autophagic vacuoles</term>
<term>Average diameter</term>
<term>Bile canaliculus</term>
<term>Biol</term>
<term>Cell biol</term>
<term>Cell diameter</term>
<term>Cell diameter measurements</term>
<term>Cell size</term>
<term>Cellular constituents</term>
<term>Control animals</term>
<term>Control livers</term>
<term>Cytoplasmic</term>
<term>Days postligation</term>
<term>Dense bodies</term>
<term>Double membranes</term>
<term>Electron micrographs</term>
<term>Electron microscope</term>
<term>Electron microscopy</term>
<term>Endoplasmic</term>
<term>Endoplasmic reticulum</term>
<term>Experimental animal</term>
<term>Experimental atrophy</term>
<term>Extracellular space</term>
<term>Fine structure</term>
<term>Focal dilatation</term>
<term>Glass slides</term>
<term>Glycogen</term>
<term>Golgi</term>
<term>Golgi apparatus</term>
<term>Hepatic</term>
<term>Hepatic cell</term>
<term>Hours postligation</term>
<term>Large clumps</term>
<term>Large vacuoles</term>
<term>Ligated</term>
<term>Ligated lobe</term>
<term>Ligated lobes</term>
<term>Ligation</term>
<term>Liquid level</term>
<term>Liver</term>
<term>Liver atrophy</term>
<term>Liver cell</term>
<term>Liver lobe</term>
<term>Liver mass</term>
<term>Lobe</term>
<term>Lysosome</term>
<term>Lysosome concept</term>
<term>Minutes postligation</term>
<term>Mitochondrion</term>
<term>Multiple membranes</term>
<term>Neutral polysaccharides</term>
<term>Nonligated</term>
<term>Nonligated counterpart</term>
<term>Nonligated counterpart lobe</term>
<term>Nonligated lobe</term>
<term>Nonligated lobes</term>
<term>Nonligated portions</term>
<term>Nonoperated controls</term>
<term>Numerous autophagic vacuoles</term>
<term>Osmium tetroxide</term>
<term>Oxygenating tube</term>
<term>Pathol</term>
<term>Phase contrast</term>
<term>Phosphate buffer</term>
<term>Portal</term>
<term>Portal supply</term>
<term>Portal vein</term>
<term>Portal vein ligation</term>
<term>Postligated lobes</term>
<term>Postligation</term>
<term>Prominent network</term>
<term>Reticulum</term>
<term>Rough endoplasmic reticulum</term>
<term>Same animal</term>
<term>Single membranes</term>
<term>Small vesicle</term>
<term>Smooth endoplasmic reticulum</term>
<term>Stellate slits</term>
<term>Time interval</term>
<term>Time postligation</term>
<term>Total liver weight</term>
<term>Trump</term>
<term>Unit area</term>
<term>Vacuole</term>
<term>Various organs</term>
<term>Various time intervals</term>
<term>Vena cava</term>
<term>Weight loss</term>
<term>Weight measurements</term>
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<front><div type="abstract" xml:lang="en">Abstract: The process of liver atrophy has been studied in an experimental model following occlusion of the portal supply to the right posterior lobe of the rat. The striking feature of these observations is the swift onset of the process of atrophy as evidenced by the rapid formation of autophagic vacuoles. Within 15 minutes there is a significant increase in the number of autophagic vacuoles. In 30 minutes, in addition, there is formation of intracellular “slits.” Autophagic vacuoles reach their peak number at 2 hours. They appear to arise from both smooth and rough endoplasmic reticulum, at first near the Golgi apparatus. Further, at 2 hours there is a significant decrease in cell size, and by the hour six there is a significant decrease in cell mass. Glycogen decreases markedly at 2 hours, but reappears in 3 to 7 days in clumps about the periphery of the cell.</div>
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Autophagic vacuoles in experimental atrophy

Autophagic vacuoles in experimental atrophy

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri